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Nexusuro
Clinical Indication — Strong Recommendation

Bladder neck contracture after TURP: a precise solution.

Post-TURP bladder neck contracture affects 5-10% of patients. TUCBDP triple-balloon dilation targets the contracture site with mechanical precision — no thermal energy, no resection, no implant.

Why TUCBDP for BNC
Clinical urology procedure room with endoscopy equipment
Understanding BNC

What is bladder neck contracture?

Bladder neck contracture (BNC) is scar tissue formation at the bladder neck after TURP, narrowing the outlet and causing recurrent obstructive symptoms — often years after the original procedure.

Incidence: 5-10% of TURP patients, higher in small prostates (<30 mL)
Symptoms: Recurrent weak stream, straining, incomplete emptying, retention, recurrent UTIs
Medical anatomical illustration of bladder neck contracture — sagittal view of lower urinary tract highlighting BNC zone

Current treatment limitations

Most existing BNC treatments carry significant trade-offs. No major commercial MIST brand has a BNC indication.

Repeat TURP incision

Cuts the scar tissue but carries high recurrence risk. Thermal energy may cause additional scarring.

Traditional balloon dilation

Single-balloon mechanical stretch without precise positioning — often provides only temporary relief.

Open reconstruction

Highly invasive surgical revision — long recovery, reserved as last resort after failed alternatives.

Triple-Balloon Precision

Why TUCBDP for BNC?

The three-balloon design uniquely addresses the precision requirements of BNC treatment — a completely unserved niche among commercial brands.

Precision targeting

Positioning balloon locks at bladder neck + anchoring balloon at distal reference point — dilation zone stays exactly on the contracture site.

No thermal, no resection

Pure mechanical dilation avoids additional scar tissue formation. Preserves remaining bladder neck tissue.

1-2 training sessions

Standardized three-step protocol. New practitioners become independent after 1-2 training sessions — versus 3-6 months for traditional techniques.

Why other MISTs can't address BNC

Every major commercial MIST brand has a structural reason for not covering post-TURP bladder neck contracture.

MIST BNC Suitability Reason
UroLift Contraindicated Permanent implants cannot be placed in post-TURP altered anatomy
Rezūm Not applicable Thermal ablation targets prostate tissue, not scar contracture
Aquablation Not applicable Waterjet targets adenoma; no BNC indication data
Optilume Unproven Paclitaxel-coated balloon has no BNC indication data
Nexusuro (TUCBDP) Strong recommendation Triple-balloon precision targeting of contracture site

Clinical evidence

Data from published peer-reviewed studies supporting TUCBDP's safety and efficacy profile.

Outcome TUCBDP Result Source
Complication rate 4.29% (vs TURP 12.86%, P=0.042) Zhang 2022 (N=140)
BNC rate (TUSP vs TURP) 2.0% vs 15.7% (P=0.031) Wang 2020
Ejaculation preserved ~95.6% (RE rate 4.45%) Gao et al. (N=265)
Long-term IPSS (38-99mo FU) 20.2 → 6.6 (67% reduction) Huang 2016 (N=565)

View complete clinical data

Managing BNC cases?

Request a product demonstration or clinical discussion about TUCBDP for bladder neck contracture.